Drug interaction with coumarin derivative anticoagulants.
نویسندگان
چکیده
منابع مشابه
Drug interaction with coumarin derivative anticoagulants. Standing Advisory Committee for Haematology of the Royal College of Pathologists.
The use oforal anticoagulants in the form ofcoumarin derivatives in the treatment of thrombosis continues to carry the risk of inducing abnormal bleeding. While the laboratory control of such treatment has been improved considerably by the introduction of standardisation (ICSH)' and the use of British comparative reagents (ACP broadsheet),' the increasing number of drugs that interact with thes...
متن کاملHistorical Data Regarding the Experiences with Coumarin Anticoagulants at the University of Wisconsin Medical School
IT'WAS 1938, 20 years ago, when, in conversation with Professor R. A. Brink of the Department of Genetics at the University of Wisconsin, that I first heard of the work beingfr done in the Department of Agriculture to identify the substance in spoiled sweet clover accountable for hemorrhagic disease in cattle. This had been initially undertaken in 1934 at the Wisconsin Agricultural Experiment S...
متن کاملHistorical data regarding the experiences with coumarin anticoagulants at the University of Wisconsin Medical School.
IT'WAS 1938, 20 years ago, when, in conversation with Professor R. A. Brink of the Department of Genetics at the University of Wisconsin, that I first heard of the work beingfr done in the Department of Agriculture to identify the substance in spoiled sweet clover accountable for hemorrhagic disease in cattle. This had been initially undertaken in 1934 at the Wisconsin Agricultural Experiment S...
متن کاملThe risk of overanticoagulation in patients with heart failure on coumarin anticoagulants.
Heart failure has been identified as a risk factor for increased coumarin anticoagulant responsiveness in several small-scale experiments. Epidemiological studies quantifying the risk of overanticoagulation by heart failure in a non-selected population on coumarins are scarce. Therefore, we investigated whether patients with heart failure have an increased risk of overanticoagulation and determ...
متن کاملProtective effects of a coumarin derivative in diabetic rats.
PURPOSE Retinal microvascular cells play a crucial role in the pathogenesis of diabetic retinopathy. The endothelial effects of cloricromene, a novel coumarin derivative, on diabetic retinopathy induced by streptozotocin (STZ) in the rat were investigated. METHODS Cloricromene (10 mg/kg intraperitoneally) was administered daily in diabetic rats, and 60 days later eyes were enucleated for loca...
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ژورنال
عنوان ژورنال: BMJ
سال: 1982
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.285.6350.1278-b